Treatment of postoperative bleeding after fondaparinux with rFVIIa and tranexamic acid.
نویسندگان
چکیده
Treatment of a haemorrhagic shock after just a single dose of fondaparinux in an orthopaedic patient with reduced renal clearance is presented. Since all routine haemostatic parameters were nearly normal, single doses of rFVIIa (90 microg/kg) and of tranexamic acid (15 mg/kg) were administered to improve thrombin generation and reduce fibrinolysis. This case is the first showing the effectiveness of combining single doses of rFVIIa and tranexamic acid in controlling severe postoperative bleeding after fondaparinux.
منابع مشابه
Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers.
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ورودعنوان ژورنال:
- The Netherlands journal of medicine
دوره 63 5 شماره
صفحات -
تاریخ انتشار 2005